Introduction: We investigated seven-year temporal trends in fosfomycin resistance among Klebsiella pneumoniae bloodstream isolates and characterized resistant isolates phenotypically and molecularly. Methods: We included 198 non-duplicate bloodstream isolates collected from hospitalized adults during 2017–2023. Fosfomy...
Nazmiye Ülkü Tüzemen, I. B. Satıcıoğlu, M. Duman et al.· Antibiotics· 0 citations
ABSTRACT The prevalence of non-susceptibility to ceftolozane-tazobactam (C/T) among Pseudomonas aeruginosa remains low, but novel mechanisms of C/T resistance are of concern. Herein, we describe a novel P. aeruginosa genotype associated with high-level C/T resistance (>256/4 µg/mL) in a single patient. Whole-genome seq...
Preeti Garai, Sophia H. Nozick, Caroline C. Jozefczyk et al.· Antimicrobial Agents and Che...· 0 citations
Circulation of diverse C. diphtheriae strains with alarming antimicrobial resistance underscores the need for genomic surveillance to evaluate transmission trends and highlights Elek test limitations in detecting toxin production and the need for improved diagnostics in low- and middle-income countries.
Sobia Khan, S. Irfan, J. Ashraf et al.· International Journal of Inf...· 0 citations
Clinical characteristics and intra-host viral evolution in pediatric patients with prolonged COVID-19 are examined, comparing immunocompetent and immunocompromised hosts, highlighting the need for continued genomic surveillance in vulnerable pediatric populations.
Charlie R. Boyle, Tien Doan, Estefany Rios-Guzman et al.· Journal of the Pediatric Inf...· 0 citations
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