Open access
Aug 2026
Compositional control of FUS condensate ageing through aggregation-prone interaction networks
This work performs equilibrium and non-equilibrium residue-resolution molecular dynamics simulations to determine how RNA and heterotypic protein interactions regulate the pathological hardening of multicomponent FUS-containing condensates inspired by stress-granule composition.
Eduardo Pedraza, Óscar Rebato, A. Feito et al.
· bioRxiv · 0 citations