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E. Vincent

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Open access Sep 2026

Connecting diet and disease: Using Mendelian randomisation to bridge the gap

Establishing causality in nutrition research is challenging. While randomised controlled trials (RCTs) provide robust evidence, long-term dietary intervention studies with disease endpoints are often impractical. Short-term RCTs can instead identify intermediate traits that may lie on the causal pathway between diet an...

B. Deslandes, L. J. Corbin, L. Goudswaard et al. · 0 citations
Open access Sep 2026

Exploring proteins as intermediates between physical activity and cancer in UK biobank

Introduction Higher physical activity (PA) is associated with lower risk of several cancers, but the biological mechanisms underlying these associations remain unclear. We integrated observational and Mendelian randomization (MR) approaches to investigate circulating proteins as potential intermediates linking PA to ca...

L. Goudswaard, M. A. Lee, L. Hobson et al. · 0 citations

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