Author

E. Trojan

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Open access Sep 2026

Treatment with Ureidopropanamide Formyl Peptide Receptor 2 Agonists Attenuates Brain Changes Induced by Systemic Lipopolysaccharide Administration in Rats

Multiple lines of evidence highlight the impact of the resolution of inflammation (RoI) on mitigating the inflammatory response and restoring homeostasis in the brain. Recently, the significance of formyl peptide receptor 2 (FPR2) in this process has been emphasized due to its remarkable ability to interact with a wide...

K. Tylek, K. Kamińska, E. Trojan et al. · ACS Omega · 0 citations

Open access Sep 2026

612. Astrocyte-mediated inflammatory response as a promising target for TRP: a study in humanized Alzheimer’s disease mice model

Abstract Background Chronic inflammation within the central nervous system is a defining feature of many neurological and neurodegenerative disorders, including Alzheimer’s disease (AD). Astrocytes, the most abundant glial cell population in the brain, play a pivotal role in maintaining neuronal homeostasis, synaptic s...

A. Basta-Kaim, E. Trojan, K. Kamińska et al. · International Journal of Neu... · 0 citations

Open access Sep 2026

613. The analysis of the impact of non-steroidal drug and the TRP compound on the immune profile of microglia: study in an Alzheimer’s disease model

Its simultaneous ability to influence the proinflammatory and anti-inflammatory profiles of microglial cells in an AD model positions this compound as a promising candidate for further investigation in the context of neuroimmune dysregulation and a tool for pharmacotherapy of resolution.

E. Trojan, K. Kamińska, M. Leśkiewicz et al. · International Journal of Neu... · 0 citations