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Open access
Oct 2026
PAI-1, MTHFR, and FVL Thrombophilic Polymorphisms as Risk Factors for Fetal Growth Restriction: A Case–Control Study from a Tertiary Care Center
In this study, PAI-1 4G/5G, MTHFR C677T, and factor V Leiden polymorphisms were independently associated with fetal growth restriction and are compatible with a contribution of hypofibrinolysis and inherited thrombophilia to the placental insufficiency phenotype, most clearly in the more severe strata.
R. Pană, Nicoleta-Loredana Anghel-Savciu, M. Dinu et al.
· Biomedicines · 0 citations