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Open access Oct 2026

GCH1 p.Ser80Asn Confers Risk for Parkinson's Disease in East Asian Populations.

INTRODUCTION GCH1 has been implicated in Parkinson's disease (PD), but its risks variants and associations are not well defined. OBJECTIVES Our goal was to investigate the clinical relevance and PD risk associated with the GCH1 p.Ser80Asn variant. METHODS We first identified a segregating GCH1 p.Ser80Asn variant in...

Yi-Wen Tay, A. Lee, J. Schee et al. · 0 citations
Open access Sep 2026

Interaction Between Cigarette Smoking and PARK16 on Parkinson’s Disease

A biologically plausible interaction between PARK16 rs6679073 and cigarette smoking in modulating PD risk is suggested and warrants further investigation.

Tze-Tsung Chong, J. Wang, E. Ng et al. · 0 citations
Open access Oct 2026

High frequency transcranial pulsed current stimulation improves quality of life in Parkinson’s disease: A randomized controlled trial

Abstract Parkinson's disease (PD) is a progressive multisystem disorder in which motor and non-motor symptoms impair quality-of-life. High-frequency transcranial pulsed current stimulation (tPCS) modulates network-level dysfunction and may serve as an adjunct therapy in PD. In a randomized controlled trial, 38 particip...

Zheng Li, Sandra Zhong, Lan Wang et al. · 0 citations

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