Author

E. Rakib

2 papers indexed here

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Open access Sep 2026

Benzothiazole–Triazole–Indazole Conjugates: Design, Characterization, and Preliminary In Vitro MTT-Based Antiproliferative Evaluation

A new library of benzothiazole–triazole–indazole conjugates (5a–s) was efficiently synthesized via a Cu(I)-catalyzed azide–alkyne cycloaddition (CuAAC) strategy. The approach involved the preparation of alkynylated indazoles and benzothiazole–azide derivatives, followed by click-chemistry cycloaddition to provide triaz...

Fatima E. Laghchioua, Maurizio Viale, Renata Silva et al. · Molecules · 0 citations

Jul 2026

Benzothiazole–Triphenylphosphonium Conjugates: Synthesis, In Silico Analysis, and Exploratory In Vitro Effects on HT‐29 Colorectal Cancer Cell Viability

The study provides an integrated workflow combining synthesis of an unreported benzothiazole–TPP scaffold, computational prioritization, and preliminary biological evaluation that identifies initial structure–activity trends within the series, establishing a foundation for future optimisation.

Fatima E. Laghchioua, Ana T. P. C. Gomes, Karina Mendes et al. · ChemMedChem · 1 citation