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Author

E. Putro

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Open access Oct 2026

Mast Cells Regulate Epithelial Barrier Integrity and Myeloid Immune Responses in Experimental Colitis.

Mast cells (MCs) are increasingly recognized as modulators of intestinal homeostasis and inflammation; however, their precise contribution during colitis remains incompletely defined. Here, we investigated the role of MCs in dextran sulfate sodium (DSS)-induced colitis using a Kit-independent MC-deficient model (Cpa3-C...

Alessia Carnevale, Caterina Marangio, E. Putro et al. · 0 citations
Open access Aug 2026

Single-cell RNA sequencing reveals pro-tumorigenic intestinal mast cell programs in colorectal cancer

These findings identify a tumor-adapted MC state that orchestrates immune evasion and tissue remodeling during CRC progression, supporting the notion that MC are reprogrammed toward an immune-suppressive and pro-tumorigenic phenotype.

E. Putro, Alessia Carnevale, Caterina Marangio et al. · 0 citations

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