Curcumin, a natural polyphenol derived from Curcuma longa, exhibits multi-targeted anti-inflammatory, antioxidant, and neuroprotective activities. This review aims to evaluate its extraction methodologies, synthetic pathways, and neuroprotective potential across preclinical and clinical paradigms, while addressing bioa...
Denise Maria Dardano, R. Macrì, Maria Serra et al.· Nutrients· 0 citations
Pesticide exposure at chronic, field-realistic doses represents a major driver of honey bee colony weakening through sublethal and synergistic effects. This narrative review synthesizes evidence from 2010 to 2025 on neurophysiological, immunological, and behavioral impacts of major insecticide classes, with emphasis on...
Roberto Bava, F. Castagna, S. Ruga et al.· Environmental Toxicology and...· 0 citations
The current environmental risk assessment framework for pesticides remains anchored to inadequate metrics and approaches. Although regulatory bodies incorporated chronic toxicity studies and developed advanced guidance, critical gaps in implementation undermine their effectiveness. Among these gaps are 1) continued pri...
F. Castagna, S. Ruga, Roberto Bava et al.· Journal of Toxicology and En...· 0 citations
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