Metabolomic profiling was applied to 1,259 sera collected within five years of a lung cancer diagnosis and 8,470 non-case sera from ever-smoker participants in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial to identify metabolic signatures for the earlier detection of lung cancer. We develop...
E. Irajizad, H. Rudsari, S. Gendarme et al.· Cell Reports Medicine· 0 citations
Biological aging occurs heterogeneously across individuals and organs. However, current measures of biological age incompletely capture organ-specific differences in health and disease risk. Because chest CT visualizes multiple thoracic organs, it offers an opportunity to quantify structural aging across organ systems....
J. Sato, M. Salehjahromi, A. Zafar et al.· medRxiv· 0 citations
Individuals with rheumatoid arthritis (RA), particularly those with a history of smoking, are at increased risk for lung cancer. However, real-world data on the use of low dose computed tomography (LDCT) screening for lung cancer in this population are lacking. Therefore, we assessed the rates, trends, and predictors o...
M. Lopez-Olivo, Zhi-Gang Duan, Hui-Fang Lu et al.· Cancer Prevention Research· 0 citations
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