Author

E. Nössner

2 papers indexed here

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Oct 2026

TCR sensitivity shapes recognition of tumor antigen presented by host cells and TCR-T cell efficacy in solid tumors.

Despite advances in adoptive T cell therapy, therapeutic efficacy in solid tumors remains inconsistent, and the mechanistic determinants of treatment failure are incompletely understood. Increasing evidence suggests that effective antitumor responses depend not only on direct recognition of malignant cells but also on...

Mete Can Odabasi, T. Kammertoens, E. Nößner et al. · Cancer immunology research · 0 citations

Open access Sep 2026

ConvexGating infers gating strategies from clusters in single cell cytometry data

Manual expert gating remains common practice for defining specific cell populations in flow cytometry data, but increasing numbers of measured parameters and high inter-rater variability limit consistency across studies. Cluster-based approaches use the full marker space to define cell populations more consistently, bu...

V. Friedrich, Karola Mai, T. Hofer et al. · Nature Communications · 0 citations