Author

E. Natali

h-index 5 View on Semantic Scholar

We have 1 of 11 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Jul 2026

Accurate ΔTm Prediction Without Protein Structure Inputs for Biomolecular Stability

It is shown that accurate ΔTm prediction does not require structural input features, but can achieve state-of-the-art results with a careful training design for large sequence-based protein language models, and choices such as loss function, pooling strategy, auxiliary supervision, and finetuning regime materially affect performance.

Daniel Siegismund, Mario Wieser, E. Natali et al. · bioRxiv · 0 citations