Open access
Jul 2026
Intrinsic flexibility of Type VII secretion central pore is required for substrate translocation
The functional roles of several central pore-forming residues in mediating secretion are probed and their crucial role in ESX-5 substrate translocation efficiency is demonstrated and shown to be general valid for these systems.
Christin Ritter, Kathrine S. H. Beckham, Grzegorz Chojnowski et al.
· bioRxiv · 0 citations