Open access
Jul 2026
Perioperative myeloid cell remodeling shapes CAR-T cell efficacy in glioblastoma
It is shown that surgical resection induces TREM2 associated immunosuppressive remodeling of the TME and CAR-T based strategies to reshape the perioperative GBM TME are tested.
Martin Pedard, Luis Castillo Cantero, Ali Ghasemi et al.
· Nature Communications · 0 citations