Enzyme kinetic parameters inform metabolic models, yet experimental measurements are sparse. A growing body of work predicts them from protein and substrate features, but software fragmentation hinders adoption, so downstream tools lock into the most accessible method. We present OpenKinetics Predictor (predictor.openk...
Saleh Alwer, Hugues Escoffier, Karim Taha et al.· bioRxiv· 0 citations
Network analysis uncovered significant differences in regulatory connectivity between AD and controls, with ZNF225, ZNF849, and ZNF548 emerging as AD-specific regulatory hubs and several key regulatory edges showed significant correlations with longitudinal cognitive decline, supporting their clinical relevance.
D. Anwer, Arina A, Agata Marchi et al.· npj Aging· 1 citation
It is claimed that Aspergillus niche evolution proceeds through directional rare genome changes, where there is expansion under pathogenic selection, and contraction under industrial domestication.
Minji Kim, Omid Ardalani, E. Kerkhoven et al.· bioRxiv· 0 citations
Aspergillus oryzae (koji mold) is a key microorganism in traditional food fermentations including soy sauce, sake, and miso and is important in novel culinary applications and modern biotechnology, such as sustainable meat alternatives and enzyme production. Despite its industrial importance, until recently, the most r...
Jeroen Gilis, C. R. B. van der Luijt, Marilena Feller et al.· Computational and Structural...· 0 citations
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