Loss of MSH6 or MSH2 sensitizes progressive glioblastoma to radiotherapy
<strong>A prime resistance mechanism of glioblastoma to temozolomide is a vulnerability to radiation therapy</strong>
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<strong>A prime resistance mechanism of glioblastoma to temozolomide is a vulnerability to radiation therapy</strong>
A unified, multi-cohort transcriptional landscape of breast cancer that organizes canonical subtypes along continuous biological axes and reveals spatially structured regions of therapeutic sensitivity and resistance is presented.
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