E. H. Althubaiti

Aberrant Transcription-Factor Expression and Regulatory microRNAs in Metastatic Breast Cancer

Metastatic breast cancer is driven by reversible cell-state programs shaped by transcription factors (TFs) and microRNAs (miRNAs). Dysregulated TFs integrate oncogenic signaling, hypoxia, inflammation, lineage identity, mechanical cues, and chromatin state, whereas miRNAs buffer or reinforce these programs through post...