Open access
Sep 2026
Chromatin context shapes SPT5 regulation of promoter-proximal Pol II, fine-tuning gene expression changes during Drosophila embryogenesis.
Different consequences of SPT5 removal at different developmental stages are uncovered using rapid optogenetic depletion in Drosophila embryos, indicating that SPT5 contributes to fine-tuning dynamic expression changes.
Alessandro Dulja, M. Mayer, Niklas L. Engel et al.
· Developmental Cell · 0 citations