A new perspective on modic type 1 changes in degenerative disc disease: a systematic evidence-based educational review.
BACKGROUND Modic type 1 changes (MC1) are magnetic resonance imaging (MRI)-defined vertebral endplate and subchondral bone marrow alterations frequently observed in degenerative disc disease (DDD). Compared with other Modic subtypes, MC1 has been more frequently associated with chronic low back pain and inflammatory fe...