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Open access Sep 2026

341. Preliminary investigation of peripheral immune markers and synaptic density in trauma-exposed youth seeking mental health treatment

Abstract Background Animal studies show that stress triggers immune dysregulation, leading to elevated levels of pro-inflammatory cytokines and microglial activation. This response is linked to excessive synaptic pruning and reduced synaptic density, potentially raising vulnerability to mental illness. In humans, child...

M. Zilberman, E. Vieira, C. Côté et al. · 0 citations
Open access Aug 2026

Brain-cognition relationships and treatment outcome in treatment-resistant late-life depression

Older adults with treatment-resistant depression are at significant risk for cognitive impairment. However, the relationship between treatment response and cognitive function in this population is not well-established. We examined neural correlates of executive and memory function, and their relationship with remission...

Peter Zhukovsky, M. Butters, H. Lavretsky et al. · 0 citations

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