Phenotype-Guided Hypertension Management in the Era of Cardiovascular–Kidney–Metabolic Syndrome: Integrating the CKM and MACARENHA Models for Personalized Dual and Triple Antihypertensive Therapy
Background: Hypertension remains the leading modifiable contributor to cardiovascular morbidity and mortality worldwide despite the availability of effective antihypertensive therapies. One of the principal limitations of contemporary management is that treatment strategies continue to focus predominantly on blood pres...