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Open access Oct 2026

Multi-Omic and Spatial Profiling Defines Outcome-Associated Tumor States in Head and Neck Adenoid Cystic Carcinoma

Head and neck adenoid cystic carcinoma (HNACC) shows highly variable clinical behavior that histopathological features only partly predict, and prognostic biomarkers for aggressive disease at diagnosis remain limited. Here, we show by integrating bulk, single-cell, and spatial transcriptomes from 25 HNACC tumors that p...

Gopikrishnan Bijukumar, Kathryn J. Brayer, Anitha Vijaykumar et al. · 0 citations
Open access Sep 2026

Quality Assurance Strategies for Brain State Characterization by MEMRI.

BACKGROUND Manganese-enhanced MRI (MEMRI) is a powerful approach for mapping brain-wide neural activity and axonal projections in vivo. Yet standardized computational frameworks for voxel-wise and atlas-based characterization of brain states across large experimental cohorts remain limited. NEW METHOD We present meth...

T. Uselman, R. Jacobs, E. Bearer · 0 citations

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