Author

E. Bari

3 papers indexed here

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Open access Sep 2026

Silk fibroin nanoparticles coated with secretome-derived extracellular vesicles via GMP-ready microfluidics: a biomimetic carrier-in-carrier platform with preferential tumor cell internalization.

The integration of synthetic nanocarriers with biologically derived membranes represents a promising strategy to engineer biomimetic systems for precision medicine. Here, we report a hybrid nanoplatform in which silk fibroin nanoparticles (SFNs) are coated with the vesicular fraction of a GMP-compliant lyosecretome (he...

Edoardo Bertania, Angelo Modena, E. Bari et al. · Journal of materials chemist... · 0 citations

Open access Sep 2026

Machine learning-assisted optimization of injectable silk fibroin hydrogels functionalized with decellularized extracellular matrix and mesenchymal stromal cell secretome.

Silk fibroin (SF) hydrogels are promising injectable scaffolds for wound repair, but optimizing their multi-parametric gelation remains challenging due to complex formulation-processing interactions. We developed a bioinspired gelation strategy combining potassium-driven β-sheet nucleation with sonication-mediated conf...

Edoardo Bertania, Angelo Modena, Maurizio Rinaldi et al. · Biomaterials Advances · 0 citations

Open access Jul 2026

Discovery of a Dual IDO1/TDO Inhibitor That Modulates Enzymatic Activity and IDO1/SHP‑2 Signaling

Compound 66 represents a chemical probe for dissecting enzymatic and signaling functions within the IDO1/TDO axis and supports small-molecule modulation of both catalytic and noncatalytic immune-metabolic pathways as an alternative to purely catalytic IDO1 inhibition or complete IDO1 degradation.

Sarah Jane Rezzi, Andrea Butticè, Salvatore Villani et al. · Journal of Medicinal Chemist... · 0 citations