Background Fungal infections are an emerging but underrecognized concern in diabetic foot ulcers (DFU); and may contribute to delaying healing and complicate clinical outcomes. This study reviewed available evidence to identify the neglected contribution of fungi to DFUs and to explore their antifungal susceptibility p...
Salma M. Alsayed, A. Khateb, Muhammad Yasir et al.· Frontiers in Fungal Biology· 0 citations
Africa harbours more than 80% of the world's dromedary camels, with a pooled MERS-CoV seroprevalence of 73·7%; however, no autochthonous outbreak in humans has been documented. In this Review, we weigh five interacting explanations for the absence of documented human outbreaks based on the strength of the evidence for...
Shreif A. El-Kafrawy, M. El-Daly, Menatalla S. El-Kafrawy et al.· The Lancet Microbe· 0 citations
Middle East respiratory syndrome coronavirus (MERS-CoV) remains a low-incidence but high-consequence zoonotic coronavirus threat. Since its identification in Saudi Arabia in 2012, more than 2600 laboratory-confirmed cases have been reported from 27 countries, most from the Arabian Peninsula; the reported case fatality...
E. Azhar, M. Alqahtani, A. Assiri et al.· International Journal of Inf...· 0 citations
Abstract Hepatitis E virus (HEV) causes over 19 million infections annually, yet the molecular determinants governing its diverse clinical phenotypes and cross-genotype immunity remain incompletely synthesized. The ORF2 capsid protein is the sole structural component of the virion, the primary neutralizing antibody tar...
Shreif A. El-Kafrawy, S. S. Putra, A. Abbas et al.· Journal of General Virology· 0 citations
El Niño creates an important opportunity for anticipatory public health action because its development can often be detected before many downstream hazards emerge. Yet predictability does not transfer uniformly from the large-scale El Niño Southern Oscillation (ENSO) signal to regional climate anomalies and ultimately...
L. Bajrai, E. Azhar· Frontiers in Public Health· 0 citations
Together, these findings identify a genetically associated inflammatory risk profile characterized by VDR risk alleles, vitamin D deficiency, and heightened inflammatory responses, providing a framework for precision risk stratification targeting the vitamin D-VDR axis.
The review highlights those circulating antibodies and neutralizing activity decline after vaccination, particularly against antigenically divergent variants, whereas memory B-cell responses and CD4+ and CD8+ T-cell immunity generally provide more durable protection against severe disease.
Leena E. Azhar, Ahdab A. Alsaieedi, M. Al Eissa et al.· Frontiers in Public Health· 0 citations
Host receptor targeting is a mechanistically rational but still clinically unproven component of the respiratory antiviral landscape; its value is most plausibly realised in defined niches—prophylaxis, early outpatient treatment, and combination with direct-acting antivirals—and within pandemic preparedness frameworks,...
S. El-Kafrawy, Norah A. Othman, M. Zeyadi et al.· Frontiers in Cellular and In...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
