Open access
Sep 2026
Unveiling structural determinants of peptide recognition by public and private SARS-CoV-2-specific T-cell receptors
Public T cell receptors (TCRs) recurrently emerge across individuals in response to common pathogens, yet the structural and biophysical basis distinguishing public from private clonotypes remains incompletely defined. Here, we combine epitope mapping, single-cell TCR sequencing, and single-particle cryo-electron m...
Caner Akıl, Yan-Chun Peng, Julia McCarthy et al.
· Nature Communications · 0 citations