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Review Open access Aug 2026

KRAS in Colorectal Cancer: Tumorigenesis, Surgical Implications and Evolving Treatment Target

Simple Summary Mutations in the Kirsten rat sarcoma viral oncogene homologue (KRAS) play an important role in colorectal cancer and are linked to higher morbidity and mortality rates while also being historically difficult to treat. This review summarises the pathophysiology which leads the mutation to tumour formation...

Sahar Iftikhar, Alexander H. Xiao, Zhao-Hui Jin et al. · 0 citations

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