SpatialJEPA: JEPA-inspired graph-context distillation for spatially aware multiomics integration
SpatialJEPA is introduced, a JEPA-inspired teacher–student framework for transferring spatial context from spatial multiomics data to non-spatial multiome data, which masks spatial context by replacing the teacher’s spatial neighborhood graph with a self-only identity graph during student training, making the spatial sample appear dissociated to the student.