Effects of Hypoxic Adipose-Derived Mesenchymal Stem Cells and Their Secretome on Type II Collagen Expression in a Rabbit Model of Disc Degeneration
Introduction: Intervertebral disc (IVD) degeneration is a major cause of low back pain, and is characterized by the loss of extracellular matrix, particularly type II collagen. Regenerative therapies using mesenchymal stem cells (MSCs) and their secretome have shown promise, but their comparative effects on type II col...