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Duy T Nguyen

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Open access Jul 2026

PRKCI-ECT2 copy number gain promotes developmental reprogramming and metastatic competence in lung adenocarcinoma

Human LUAD analyses support these progenitor programs as clinically relevant features of PRKCI-ECT2 gain and show that elevated PKCι-ECT2 signaling rewires tumor trajectory in a cell-of-origin-dependent manner.

Duy T Nguyen, Kayleah M Meneses, Cheng Zhang et al. · Cell Reports · 0 citations