Open access
Sep 2026
Design-of-experiments-assisted microfluidic synthesis of sorafenib nanocrystals for improved oral bioavailability.
Overall, microfluidic nanoprecipitation combined with DoE optimisation offers a robust and scalable strategy for producing high-quality ST-NCs with controlled size, stable solid-state properties, and improved pharmaceutical performance.
Ji-Chao Dai, Heba Allah Abou Swid, Randa Zoqlam et al.
· International journal of pha... · 0 citations