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Dr. R. SUNDARARAJAN, S.G. RAMAN, P. RAJAKUMAR, A. RAJKUMAR, RASHID.R, J. SATHISH KUMAR, M.YOKESHWARAN

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#edge computing Open access Sep 2026

BERBERINE ENGAGES A SEROTONERGIC–MONOAMINERGIC AND JAK/PI3K MULTI-TARGET AXIS IN BREAST CANCER: AN INTEGRATED NETWORK PHARMACOLOGY STUDY

Abstract— Berberine, a quaternary protoberberine alkaloid of Berberis and Coptis species, showsreproducible anti-proliferative activity in breast cancer models, but the experimental literature isfragmented across unrelated pathways and no prioritised target map exists. This study converts thatscattered evidence into a...

Dr. R. SUNDARARAJAN, S.G. RAMAN, P. RAJAKUMAR, A. RAJKUMAR, RASHID.R, J. SATHISH KUMAR, M.YOKESHWARAN · 0 citations

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