Author

Douglas E. Brackney

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Open access Sep 2026

Interdependent RNA structural motifs at the 3′-terminus of the West Nile virus genome regulate viral growth

Abstract The RNA genome of West Nile virus (WNV) folds into an elaborate series of RNA structural elements that are crucial for viral function. Among these elements, four pseudoknots (PKs) at the viral 3′-terminus, designated as SLII, SLIV, DBI, and DBII, are among the most crucial players in the overall flaviviral lif...

Lucille H. Tsao, Douglas E. Brackney, A. Pyle · Nucleic Acids Research · 0 citations

Open access Aug 2026

Adaptive Sequencing Resolves Bacterial Genomes from the Mosquito Microbiome: Linking Function to Larval Development

Adaptive sequencing was employed as a host DNA depletion approach to improve microbial sequence recovery from Aedes aegypti larvae. This methodology was applied to a colonization experiment where axenic larvae were reared in water collected from three habitats allowing for microbial colonization. Both cultivation and...

Jing Yuan, Jacquelyn C. LaReau, Douglas E. Brackney et al. · ISME Host Microbe · 0 citations