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Dou-Dou Zhou

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Open access Oct 2026

Deciphering Spatial Cellular Organization through RNA-Anchored Multi-Omics Deconvolution

Spatial technologies that jointly profile RNA and additional molecular layers provide a comprehensive view of tissue organization, yet their limited resolution results in measurements that reflect mixtures of multiple cell types. While RNA-based deconvolution methods are well established, incorporating co-profiled non-...

Yi-Hao Bai, Xin Guan, Shu-Cun Xiong et al. · 0 citations
Preprint Aug 2026

Inferential Evaluation of Surrogate-Derived Models under Covariate Shift

Cross-fitted estimators that transport information from the two labeled sources through source-specific density ratios are proposed that establish asymptotically linear inference for TPR and FPR, consistency and pointwise inference for the ROC curve, and asymptotically normal inference for AUC.

Long-Tian Shi, Molei Liu, Dou-Dou Zhou · 0 citations
Preprint Jul 2026

Personalizing Large Language Model Agents with Small Policy Models

This work forms personalization of a frozen agent as online learning of a per-user execution policy from scalar feedback observed only for the executed action, and proposes FABLE (Factorized Adaptive Bandit Layer for Execution), a lightweight policy layer outside a potentially black-box host agent.

Dian Jin, Zhi Zhang, Huichao Li et al. · 0 citations

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