Author

Dorothy P. Schafer

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Open access Aug 2026

Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in a mouse model for post-streptococcal encephalitis

Group A Streptococcus (GAS) infections cause neuropsychiatric complications in children, but the mechanisms linking peripheral infection to brain dysfunction remain unclear. Using mouse genetics, single-cell RNA sequencing, and spatial transcriptomics, we show that GAS infections induce inflammatory transcriptional pro...

C. R. Wayne, U. Akcan, Travis E. Faust et al. · Nature Communications · 0 citations

Review Jul 2026

Glia orchestrate neural circuit development.

Evidence is synthesized for the multifaceted functions by which glial cells instruct neuronal circuit establishment and maturation across developmental stages and in both vertebrate and invertebrate nervous systems.

K. Sakers, Patrick W. Sheehan, Wendy Xin et al. · Developmental Cell · 1 citation