Control charts with parameter estimates from small Phase I samples are at risk of providing inaccurate signals due to poor model fit. In turn, Guaranteed In‐Control Performance (GICP) approaches were introduced to account for the resulting variability in the conditional average run length. Combined GICP and Cautious Learning (GICP/CL) procedures were then proposed to mitigate the loss in sensitivity associated with GICP approaches. However, the performance of GICP/CL approaches is hitherto not fully explored. Previous research suggests that the convergence rate of the standard error, that is commonly used to adapt the control limits in GICP/CL frameworks, results in an unwanted gradual loss of detection power. This study explores the issue and shows that, when using the convergence rate of the standard error to adapt control limits, control charts calibrated for GICP have their sensitivity gradually decreased due to high variability in IC performance. Causes of high variability in the IC performance are small Phase I samples and low parameter updating frequencies. An alternative control limit adaption rate for steady GICP performance is proposed and recommendations for practical application are put forward.
Alexander Wendler, V. Tercero-Gómez, Dongping Du et al.· Quality and Reliability Engi...· 0 citations
A deeper understanding of genetic architecture, environmental exposures, and sociocultural factors appear to contribute to earlier onset and more aggressive disease, suggesting an urgent need for South Asian specific HF risk prediction models.
Nandini Nair, Dongping Du, Aiswarya J. Pillai et al.· Journal of Clinical Medicine· 0 citations
This multimodal approach identifies high-risk phenotypes, specifically right-heart and systemic frailty, providing a framework for personalized clinical decision support and future multicenter validation.
Gabriel Farias Cacao, Dongping Du, Nandini Nair· International Journal of Art...· 0 citations
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