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Donggyun Kim

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Open access Aug 2026

Structural basis of endogenous lipid recognition and G protein selectivity in GPR119

G protein-coupled receptors (GPCRs) often engage multiple intracellular transducers, yet the structural basis by which endogenous ligands influence G protein selectivity remains poorly understood. GPR119 is a lipid-activated receptor expressed in pancreatic β-cells and enteroendocrine L-cells, where it regulates glucos...

Donggyun Kim, Mohsen Ranjbar, Aleksey Raskovalov et al. · 0 citations

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