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Author

Dongyuan Zhu

2 papers indexed here

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Review Open access Aug 2026

HLX07, a novel anti-EGFR antibody, for locally advanced and metastatic cutaneous squamous cell carcinoma: an open-label, multicenter, phase II trial

Background: Cutaneous squamous cell carcinoma (CSCC) accounts for 20% of all cutaneous cancers. Systemic treatment options for advanced CSCC (aCSCC) include immunotherapy, chemotherapy, and epidermal growth factor receptor (EGFR)-targeted therapy, although their efficacy is limited. HLX07 is a novel anti-EGFR antibody...

Chang-Xing Li, Kang Zeng, Dong-Yuan Zhu et al. · 0 citations
Open access Aug 2026

Integrative cfDNA profiling from low-pass whole-genome sequencing enables tissue-of-origin prediction in cancer

Cancer type classification is challenging due to tumor heterogeneity and undefined tissue of origin (TOO), particularly in cancers of unknown primary (CUP) and multiple primary cancers (MPC). Accurate TOO identification is critical for guiding treatment and prognosis. We developed a stacked ensemble machine learning cl...

Yunjian Zhang, Liang Liu, H. Bao et al. · 0 citations

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