Tumor immune evasion is shaped not only by canonical immune checkpoints but also by lysosomal stress adaptation, autophagy, metabolic remodeling, and therapy-induced survival programs within malignant cells. Lysosomal-associated protein transmembrane 4 beta (LAPTM4B), an oncogenic lysosomal transmembrane protein, h...
Hao-Kun Leng, Ze-Tong Zheng, Rui-Zheng Li et al.· Frontiers in Immunology· 0 citations
Uncoordinated homeobox (UNCX) is upregulated in docetaxel-resistant breast cancer cells, genomically amplified in breast cancer, and associated with poor survival in breast carcinoma patients, and established as a pivotal epigenetic regulator of TNBC progression and chemoresistance.