Dong-Shun Ni

Asymmetric Alkylation of α-Cyanoketimines with Alkyl Bromides Catalyzed by Bis-Cinchonium Salts

The SN2 reaction constitutes one of the most fundamental bond-forming transformations in organic chemistry, finding numerous synthetic applications across pharmaceutical, agrochemical, and materials science. However, the development of new catalysts for asymmetric SN2 reactions with nucleophiles beyond enolate deriva...