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Safety of ozanimod and etrasimod in ulcerative colitis
Ozanimod and etrasimod are sphingosine-1-phosphate receptor modulators approved for ulcerative colitis treatment. Given their limited real-world safety data in this specific population, we conducted a disproportionality analysis using the Food and Drug Administration Adverse Event (AE) Reporting System database, aiming...
Preclinical pharmacological effects of epimedium-derived interventions in osteoarthritis: a systematic review and meta-analysis
Botanical metabolites derived from the genus Epimedium demonstrate pharmacological potential in Murine models of OA and likely involve attenuating the production of systemic and local inflammatory factors and ameliorating cartilage damage.