Oct 2026
Copper-catalyzed synthesis of N-γ-lactam-substituted sulfoximines via radical cascade cyclization.
Existing approaches to sulfoximine N-alkylation rely on N-nucleophilic substitution or direct radical trapping at nitrogen, which are hampered by harsh conditions or restricted reaction modes. Herein, we report a distinct strategy for radical N-alkylation through a copper-catalyzed radical cascade. The transformation p...
Ze-Guo Fang, Di Yang, Han-Yang Zhang et al.
· Organic and biomolecular che... · 0 citations