The ARLA1A-NAC089 module coordinates ER phagy with the unfolded protein response to maintain cellular homeostasis in plants.
The endoplasmic reticulum (ER) is a critical quality-control organelle for protein homeostasis within the cell. The accumulation of misfolded or unfolded proteins triggers ER stress, which can be alleviated through the unfolded protein response (UPR) and ER phagy. These processes work in concert to preserve ER homeosta...