Dong-Hwee Kim

Mechanoresponsive reprogramming of tumor-associated macrophages during cancer progression

Tumor-associated macrophages (TAMs) are critical regulators of the tumor microenvironment. They exhibit diverse pro-tumorigenic and antitumor phenotypes depending on their monocyte-derived or tissue-resident origins. Beyond biochemical signaling, the mechanical properties of the tumor microenvironment, including extrac...