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Dong-Dong Huang

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Open access Sep 2026

PRKX-mediated stabilization of PD-L1 characterizes an immunosuppressive gastric cancer subtype

Abstract Background Gastric cancer (GC) derives limited benefit from immunotherapy, with clinical responses observed in only a minority of patients. Increasing evidence suggests that heterogeneity within the tumor immune microenvironment (TME) is a critical determinant of immunotherapeutic efficacy, highlighting the ne...

Qi-Yue Wang, Yin-Qi Chen, Dong-Dong Huang et al. · 0 citations

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