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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Domenico Mavilio

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Review Open access Aug 2026

Programmed cell death-1: from a T-cell immune checkpoint to a regulator of Natural Killer cell biology

Programmed cell death protein 1 (PD-1, CD279) is a pivotal inhibitory immune checkpoint receptor that plays a central role in maintaining immune homeostasis and peripheral tolerance. Originally characterized as a negative regulator of T-cell activation, PD-1 limits excessive immune responses and prevents autoimmunity,...

Fabiana De Franco, Marco Greppi, Valentina Obino et al. · 0 citations

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