#protein folding
Sep 2026
Antibody Hotspot-Centric de Novo Design of Peptide Inhibitors of Influenza A Virus Membrane Fusion
It is demonstrated that hotspot-guided design strategy, previously applied to proteins and d-peptides, can be effectively extended to l-peptide scaffolds, enabling the development of functional HA inhibitors informed by key residues at antigen–antibody interfaces.
R. U. Kadam, J. Juraszek, D. Branduardi et al.
· ACS Medicinal Chemistry Lett... · 0 citations