Dini Attala Hefa Insyira

Chemical Profiling and In Silico Study of Russelia equisetifomis Major Phytochemicals as Potential Dual-Site Acetylcholinesterase Inhibitors in Alzheimer’s Disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory impairment, associated with cholinergic dysfunction and β-amyloid aggregation. Acetylcholinesterase (AChE) plays a dual role in AD progression by hydrolysing acetylcholine (ACh) at the catalytic active sit...