The role of platelet-rich plasma and stem cells in the management of osteoarthritis: Current evidence, clinical positioning, and translational challenges.
Platelet-rich plasma (PRP) and mesenchymal stromal cell (MSC) therapies are among the most widely used regenerative interventions for knee osteoarthritis (OA). Despite being driven by a broadly similar regenerative concept, important differences in biological characteristics, evidence availability, and regulatory requi...