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Dijanneliz Acosta

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Review Open access Sep 2026

Role of the Gut Microbiome in Natural and Synthetic Drug Efficacy and Safety: A Narrative Review

The gut microbiome has emerged as an important determinant of the metabolism, efficacy, and safety of many therapeutic agents, expanding the traditional host-centered view of pharmacology. Direct microbial biotransformation is particularly relevant to orally administered compounds, whereas the gut microbiome can also i...

Ricardo Villoch-Rosado, Dijanneliz Acosta, Lorelein Morales-Santiago et al. · 0 citations

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