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Author

Diane L. Maresco-Pennisi

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2 papers indexed here

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Open access Sep 2026

Population pharmacokinetics of piperacillin/tazobactam in critically ill pediatric patients

ABSTRACT Piperacillin-tazobactam is commonly used in critically ill pediatric patients; however, standard dosing regimens may not reliably achieve maximally effective exposures in this population. To characterize the population pharmacokinetics of piperacillin-tazobactam in critically ill pediatric patients and evaluat...

T. Dorofaeff, M. P. Hernández-Mitre, Xin Liu et al. · 0 citations
Open access Sep 2026

Vancomycin population pharmacokinetics and optimized dosing in critically ill infants and children.

BACKGROUND Vancomycin dosing remains challenging due to narrow therapeutic window and pharmacokinetic (PK) variability in critically ill children. This study aims to characterise pediactric vancomycin PK, identify significant covariates, and optimise dosing strategies. METHODS Vancomycin plasma concentrations from pa...

T. Dorofaeff, Xin Liu, E. Novy et al. · 0 citations

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